What do you guys do if you suddenly have to switch to an amp instead of a PA? Do you go to each preset, turn the cabinets off and resave them all? Could you actually load your setups in icloud or something and quickly grab them if you need to switch? Sounds like a global switch like in Line 6 stuff or bias fx might be handy
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I get using the sim for pedals or maybe just to tweak the sound but then it's really up to your ear and taste to adjust things. Make sense?
Some of the pedalboards out there, like much of the line 6 stuff, require you to do a little bit of trickery to get these separate signals, while others have them natively.
While every single destination as you say definitely need to be tweaked for 100% perfection, full range speakers vs guitar speakers are two completely different categories, one which is perfectly happy (optimal even) with the sound you give it, the full range speaker is almost without exception (never say never, kids are crazy!) an utter nightmare without some filtering done to make it sound like the bandlimited guitar voiced speaker setup.